◆ Gentoo Logic · Modeling Warehouse

Biotech · AI architecture

5 Biotech companies — how they build with AI

How Biotech companies build with AI — which foundational models they run and how directly, ranked by proximity to the model. Avg Foundation Proximity Score 100/100.

Native 5Direct API 0Cloud-hosted 0Middleware 0

EvolutionaryScale

Biotech · AWS · Native (own / self-hosted weights)

EvolutionaryScale operates ESM3 as a proprietary, GPU-accelerated protein LLM stack on AWS, exposing commercial access primarily via AWS SageMaker, AWS HealthOmics, and soon Amazon Bedrock, while distributing a smaller open version of ESM3 and earlier ESM models with code and some weights on GitHub and Hugging Face for non-commercial and open use.[3][5][7][11] Internal architecture details beyond this cloud/HPC and PyTorch-centric GPU cluster setup are not publicly documented.[3][10][12]

Ginkgo Bioworks

Biotech · AWS · Native (own / self-hosted weights)

Cell-programming foundry training its own biological/sequence models over massive lab data.

Insilico Medicine

Biotech · Multi-Cloud · Native (own / self-hosted weights)

Generative-chemistry drug discovery on its own target-discovery + molecule-generation models.

Isomorphic Labs

Biotech · GCP · Native (own / self-hosted weights)

Public materials indicate Isomorphic Labs runs its production AI/drug-design engine on Google Cloud, using Google Cloud AI Hypercomputer with TPU/GPU fleets orchestrated by Google Kubernetes Engine for autoscaling inference workloads. The company publicly emphasizes its own drug-design engine and AlphaFold-derived models rather than exposing a foundational LLM-centric stack.

Recursion

Biotech · GCP · Native (own / self-hosted weights)

Drug discovery on its own phenomics foundation models trained over petabytes of cellular imaging.

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